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ESRD overview

What is ESRD?

ESRD, End Stage Renal Disease, occurs when chronic kidney disease developed into an advanced state which is after kidney failure. In this stage, your kidney function is less than 15% that can not meet body's needs. In this stage, toxins and extra fluids will build up in your body and cause symptoms.

What happened in ESRD?

As chronic kidney disease progresses to end-stage renal disease, signs and symptoms might include:

Nausea

Vomiting

Loss of appetite

Fatigue and weakness

Sleep problems

Changes in how much you urinate

Decreased mental sharpness

Muscle twitches and cramps

Swelling of feet and ankles

Persistent itching

Chest pain, if fluid builds up around the lining of the heart

Shortness of breath, if fluid builds up in the lungs

High blood pressure (hypertension) that's difficult to control

Signs and symptoms of kidney disease are often nonspecific, meaning they can also be caused by other illnesses. Because your kidneys are highly adaptable and able to compensate for lost function, signs and symptoms may not appear until irreversible damage has occurred.

What cause ESRD?

Diseases and conditions that can lead to kidney disease include:

Type 1 or type 2 diabetes

High blood pressure(Hypertension)

Glomerulonephritis, an inflammation of glomeruli

Interstitial nephritis, an inflammation of the kidney's tubules and surrounding structures

Polycystic kidney disease

Prolonged obstruction of the urinary tract, from conditions such as enlarged prostate, kidney stones and some cancers

Vesicoureteral reflux, a condition that causes urine to back up into your kidneys

Recurrent kidney infection, also called pyelonephritis

ESRD

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