Can You Only Change Medication When Proteinuria Gets Relapse Frequently

2019-03-28 17:23

Can You Only Change Medication When Proteinuria Gets Relapse FrequentlyIn the course of kidney disease treatment, many patients have the problem of repeated proteinuria attacks. When most patients encounter such problems, the first solution is to change medicines or increase the dosage of drugs to stabilize proteinuria so as to prevent the disease getting worse.

However, although some patients adjust the treatment plan or improve the medication in time, the level of proteinuria is still fluctuating and unsatisfactory. Why does this happen? In the final analysis, the fundamental reason for the recurrence of proteinuria is that kidney patients have not found out. Simply to change the medication can not treat the disease from the root.

After proteinuria is elevated, don't rush to change the medication. The key is to do two things well, which many patients do not realize:

1. Finding the reasons for recurrence of proteinuria

Although proteinuria is a product of impaired renal function, some patients maintain proteinuria at about 0.5g for a long time, but suddenly rise to 3g. Obviously, there are acute progression factors. If you only use medicines for renal function, it is hardly for you to achieve a satisfied effect.

There are three main causes of proteinuria attack:

(1) Repeated infections. Because the immunity of kidney patients is generally low, they are prone to infections, such as respiratory infections, cold, oral infections such as periodontitis, urinary infections such as hydronephrosis. So if proteinuria suddenly rises, check if there is an infection.

(2) Inappropriate diet. Patients with proteinuria need to adhere to a low amount of high-quality protein diet and low-salt diet for a long time to ensure protein balance, stabilize immunity and alleviate edema. However, some patients can not persist for a long time. Too much high-protein and high-salt food intake invisibly increases the burden of the kidney and inevitably causes the recurrence of proteinuria.

(3) Improper medicine intake. Steroid is the main medicine of anti-inflammatory and protein-lowering, but some patients take incorrect medication, leading to inadequate anti-inflammatory efforts, which will also cause the recurrence of proteinuria.

If before proteinuria reduction treatment, the infection factors should be eliminated and diet should be adjusted firstly to observe the proteinuria, and the therapeutic effect of proteinuria-lowering is often obvious. For the relapse of proteinuria caused by improper medication, it can be treated by improving medication.

2. In addition to steroids, traditional Chinese medicine can also be used.

In the early stage of kidney disease, renal function is damaged slightly and protein leakage is little. If treated promptly, proteinuria could be completely inhibited. However, with the progress of renal function, protein leakage is increasing. Although steroid + immunosuppressive agents have some control effect, it is difficult to recover completely. In addition to proteinuria, in order to stabilize the condition, it is more important to maintain the stability of renal function.

To maintain the stability of renal function, on the one hand, to eliminate kidney inflammation, on the other hand, to clean up toxins in time. Steroids play a limited role in anti-inflammation and do not have the effect of eliminating toxins, which leads to the resurgence of immune inflammation. Traditional Chinese medicine (TCM) has relatively small side effects and obvious effects of dredging blood vessels and removing toxins. Therefore, it can be used as an adjunct to steroid therapy to inhibit immune inflammation and stabilize renal function to reduce proteinuria.

Different pathological types of kidney disease have limitations on the quantification of proteinuria. Active treatment of proteinuria can mostly recover in light and early pathological types of nephropathy, including membranous nephropathy stage 1 and 2, early stage of IgA Nephropathy and minimal change nephropathy. However, for patients who have developed renal insufficiency or even renal failure, it is unrealistic to require a complete reversal of proteinuria.

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