Two Medicine for Reducing Proteinuria, Protecting Renal Function and Preventing Complications

2018-09-07 15:31

Two Medicine for Reducing Proteinuria, Protecting Renal Function and Preventing ComplicationsThere are two medicines for kidney patients to reduce proteinuria, protect renal function and prevent complications. Have you tried them before?

Reducing fat and preventing cardiovascular complications - statins

Statins are commonly used drugs for lowering cholesterol level. It can not only reduce total cholesterol and low density lipoprotein, but also reduce the accumulation of lipoprotein in glomerular mesangial area and renal tubule interstitial so as to improve renal function including filtration function, achieving the purpose of lowering proteinuria and protecting renal function.

Some kidney patients also have high blood lipids. Stabilizing blood lipid can reduce the burden on the kidneys, while reducing the incidence of cardiovascular diseases. Cardiovascular disease is a common complication in the advanced stage of kidney disease, and its harm is far greater than renal failure, because it can increase the death risks of renal patients. The use of these drugs can protect kidney function and prevent complications.

The commonly used statins include lovastatin, simvastatin, pravastatin, resuvastatin, fluvastatin and atorvastatin.

Regulating calcium and phosphorus metabolic disorders, and treating renal bone disease - active vitamin D

When renal function is damaged, electrolytes will be disordered. As the disease progresses slowly, some patients will have blood phosphorus metabolism disorder. The increase of phosphorus in the blood will lead to the decrease of blood calcium, which will easily lead to bone diseases such as osteoporosis, severely affecting the life of patients and decreasing their living quality.

One of the drugs commonly used in the treatment of renal osteopathic diseases is alfacalcidol, an "active vitamin D". By correcting calcium and phosphorus metabolic disorder, increasing blood calcium level and decreasing parathyroid hormone level, bone disease can be prevented.

In fact, active vitamin D also has the effect of lowering proteinuria, protecting kidney function, do you know?

Domestic medical institutions conducted group comparison therapy for IgA Nephropathy patients with urinary protein, which was divided into "calcitriol treatment group" and "non-use calcitriol treatment group". The results of comparative analysis showed that the calcitriol group could reduce the level of proteinuria by 19%. There was no significant difference in the incidence of side effects between the two groups during treatment.

A comprehensive analysis of the results of a similar study is also available in the foreign journal JASN. They included six randomized controlled trials and analyzed the results to show that active vitamin D decreased proteinuria by 16 percent.

This suggests that active vitamin D, in addition to treating bone disease, reduces proteinuria and further slows the progression of renal function.

These drugs are not suitable for all kidney patients. You must strictly follow your doctor’s instructions. Do not use medicines blindly. Only when you use the medicine correctly can you have a good effect. For more information on CKD and its symptom treatment, please leave a message below or contact online doctor.

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